In every study conducted so far, ubiquinol has been shown to be far more bioavailable than the non-reduced form (CoQ10). Dr. Steven Sinatra,cardiologist and founder of the New England Heart Center, recommends taking at least 100 milligrams (mg), but preferably 200 mg of high-quality CoQ10 or ubiquinol daily.
One study in the European Journal of Pharmacology showed that ubiquinol effectively rescued cells from the damage caused by the statin drug simvastatin, thereby protecting muscle cells from myopathies.4
The other part most people don’t realize is that CoQ10 and ubiquinol are lipid-soluble materials biosynthesized in your blood. The carrier is the blood lipid cholesterol.
The ubiquinol actually keeps your LDL (often referred to as the “bad” cholesterol) reduced, as it’s an exceptionally potent antioxidant.
Reduced LDL cholesterol isn’t bad cholesterol at all. Only the oxidized version will cause a problem. So by reducing CoQ10 production in your body, you’re also removing the mechanism that keeps your LDL cholesterol from doing harm in your body.
3. Statins Reduce Vitamin K2
A finding was published in March 2015, and it is not yet widely known.
Research published in Expert Review of Clinical Pharmacology revealed that, in contrast to the current belief that cholesterol reduction with statins decreases atherosclerosis, the drugs may instead actually stimulate atherosclerosis and heart failure.5
There were several physiological mechanisms discussed in the study that show how statin drugs may make your heart health worse, one being that they inhibit the synthesis of vitamin K2. Vitamin K2 protects your arteries from calcification. Without it, plaque levels worsen.
Vitamin K2’s biological role is to help move calcium into the proper areas in your body, such as your bones and teeth. It also plays a role in removing calcium from areas where it shouldn’t be, such as in your arteries and soft tissues.
According to a 2009 Dutch study, vitamin K2 is associated with reduced vascular calcification even at small dietary intakes.